Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test

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The search continues for possible interventions that delay and/or reverse biological aging, resulting in extended healthspan and lifespan. Interventions delaying aging in animal models are well established; however, most lack validation in humans. For the full study, click here.

Can We Live to 200?

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In the last century, the average human life expectancy doubled. Here’s a roadmap to the innovations that could help us do it again — maybe. By Nicholas St. Fleur, Chloe Williams and Charlie Wood The New York Times looks at interventions to address aging. We are the only commercially available product on the market with data showing a positive effect on healthspan and lifespan. The first suggestion in the article references the work we’ve done with Rejuvant.

Healthy Aging from the Inside Out

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A recent study suggests calcium alpha-ketoglutarate could positively affect aging, with increases in lifespan, a reduction in frailty, and increase in healthspan.  Read full article…

Alpha-Ketoglutarate Extends Healthspan in Aging Mice

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A research team led by Dr. Brian Kennedy has shown that administration of alpha-ketoglutarate (AKG), a natural metabolite in the citric acid cycle, improves both lifespan and healthspan in middle-aged mice. Read full article…

An Interview with Brian Kennedy of the Center for Healthy Aging in Singapore

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Brian Kennedy formerly headed the Buck Institute, but these days can be found leading the Center for Healthy Aging at the National University of Singapore. The Life Extension Advocacy Foundation staff recently had a chance to conduct an interview, and you should read the whole thing. Kennedy has an interesting view of the field, for all that he is largely focused on calorie restriction mimetic approaches that, to my eyes, are not likely to produce large enough benefits to really change the trajectory of human aging. Read Full Article…

Ponce De Leon Health launches an innovative supplement to “resist” biological aging

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Ponce De Leon Health (Fernandina Beach, FL) has launched a product under that brand name Rejuvant called LifeTabs, a dietary supplement with formulations for men and women designed to “resist aging.” The product contains a patent pending formulation of Calcium Alpha-Ketoglutarate (brand name LifeAKG), which is generally recognized as safe. Read Full Article…